Clinical Decision Support Tools to Prevent VTE Increase Correct Therapy Choices

Adult trauma patients whose care included the use of mandatory clinical decision support (CDS) tools to prevent venous thromboembolism (VTE) received a greater amount of appropriate preventive therapies, a recent AHRQ-funded study has found. To improve best practices in VTE prevention, researchers implemented a mandatory computerized provider order entry tool and evaluated a checklist of VTE prevention best practices against each patient’s pharmacological and risk profile. Providers were prompted to order VTE prevention measures based on each patient’s level of risk. The study, “Improved Prophylaxis and Decreased Rates of Preventable Harm With the Use of a Mandatory Computerized Clinical Decision Support Tool for Prophylaxis for Venous Thromboembolism in Trauma,” appeared in the October issue of Archives of Surgery. Select to access the abstract on PubMed.®

Arch Surg. 2012 Oct;147(10):901-7. doi: 10.1001/archsurg.2012.2024.

Improved prophylaxis and decreased rates of preventable harm with the use of a mandatory computerized clinical decision support tool for prophylaxis for venous thromboembolism in trauma.

Haut ER, Lau BD, Kraenzlin FS, Hobson DB, Kraus PS, Carolan HT, Haider AH, Holzmueller CG, Efron DT, Pronovost PJ, Streiff MB.

Source

The Armstrong Institute for Patient Safety; Division of Acute Care Surgery, Departmen of Surgery, The Johns Hopkins Hospital, Baltimore, MD, USA. ehaut1@jhmi.edu

Abstract

OBJECTIVE:

Venous thromboembolism is associated with substantial morbidity and mortality and is largely preventable. Despite this fact, appropriate prophylaxis is vastly underutilized. To improve compliance with best practice prophylaxis for VTE in hospitalized trauma patients, we implemented a mandatory computerized provider order entry-based clinical decision support tool. The system required completion of checklists of VTE risk factors and contraindications to pharmacologic prophylaxis. With this tool, we were able to determine a patient's risk stratification level and recommend appropriate prophylaxis. To evaluate the effect of our mandatory computerized provider order entry-based clinical decision support tool on compliance with prophylaxis guidelines for venous thromboembolism (VTE) and VTE outcomes among admitted adult trauma patients.

DESIGN:

Retrospective cohort study (from January 2007 through December 2010).

SETTING:

University-based, state-designated level 1 adult trauma center.

PATIENTS:

A total of 1599 hospitalized adult trauma patients with a hospital length of stay greater than 1 day.

MAIN OUTCOME MEASURES:

The primary outcome measure was the proportion of patients who were ordered risk-appropriate guideline-suggested VTE prophylaxis. The secondary outcome measure was the proportion of patients with any preventable VTE (defined as VTE in a patient not ordered guideline-appropriate VTE prophylaxis), pulmonary embolism, and/or deep vein thrombosis.

RESULTS:

Compliance with guideline-appropriate prophylaxis increased from 66.2% to 84.4% (P < .001). The rate of preventable harm from VTE decreased from 1.0% to 0.17% (P = .04).

CONCLUSIONS:

Implementation of a mandatory computerized provider order entry-based clinical decision support tool significantly improved compliance with VTE prophylaxis guidelines in hospitalized adult trauma patients. This improved compliance was associated with a significant decrease in the rate of preventable harm, which was defined as VTE events in patients not ordered appropriate prophylaxis.