jueves, 12 de noviembre de 2015

Unresolved Pain Interference among Colorectal Cancer Survivors: Implications for Patient Care and Outcomes. - PubMed - NCBI

Unresolved Pain Interference among Colorectal Cancer Survivors: Implications for Patient Care and Outcomes. - PubMed - NCBI



 2015 Jul;16(7):1410-25. doi: 10.1111/pme.12727. Epub 2015 Mar 20.

Unresolved Pain Interference among Colorectal Cancer SurvivorsImplications for Patient Care and Outcomes.

Abstract

OBJECTIVE:

Using a large sample of colorectal cancer (CRC) survivors we 1) describe pain interference (PI) prevalence across the cancercontinuum; 2) identify demographic and clinical factors associated with PI and changes in PI; and 3) examine PI's relationship with survivors' job changes.

METHODS:

CRC participants of the Cancer Care Outcomes Research and Surveillance Consortium completed surveys during the initial phase ofcare (baseline, < 1 year, n = 2,961) and follow-up (about 1-year postdiagnosis, n = 2,303). PI was measured using the SF-12 item. Multiple logistic regression was used to identify predictors of PI. Model 1 evaluated moderate/high PI at baseline, Model 2 evaluated new/continued/increasing PI postdiagnosis follow-up, and Model 3 restricted to participants with baseline PI (N = 603) and evaluated predictors of equivalent/increasing PI. Multivariable logistic regression was also used to examine whether PI predicted job change.

RESULTS:

At baseline and follow-up, 24.7% and 23.7% of participants reported moderate/high PI, respectively. Among those with baseline PI, 46% had equivalent/increasing PI at follow-up. Near diagnosis and at follow-up, female gender, comorbidities, depression, chemotherapy and radiation were associated with moderate/high PI while older age was protective of PI. Pulmonary disease and heart failure comorbidities were associated with equivalent/increasing PI. PI was significantly associated with no longer having a job at follow-up among employed survivors.

CONCLUSION:

Almost half of survivors with PI during the initial phase of care had continued PI into post-treatment. Comorbidities, especially cardiovascular and pulmonary conditions, contributed to continued PI. PI may be related to continuing normal activities, that is, work, after completed treatment.
© 2015 American Academy of Pain Medicine. © 2015 Wiley Periodicals, Inc.

KEYWORDS:

Colorectal Cancer; Comorbidity; Pain Interference; Survivor; Work

PMID:
 
25799885
 
[PubMed - in process] 
PMCID:
 
PMC4504768
 [Available on 2016-07-01]

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